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The lock actuators are a frequent failure point on both the gen5 and gen6 Altimas. There's no separate fuse for the driver's door, so if the other 3 work then it's almost certainly a bad actuator. The actuators aren't replaceable separately, you'll need a new Lock Assembly.
 

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2022 Altima SV
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That looks right and the p/n matches what it should be for a gen5 driver's door, so I don't see why it wouldn't work (other than maybe China craftsmanship). The only bear about changing them is that the outside handle needs to come out, you can't connect the cable with it in place.
 

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found this which I thought was great.

also saw where a guy took out the door handle, as you said, to get to the latch. Anyhow both jobs looked okay to do. Had to replace the window regulator on BMW and compare that to this? ithis is an easy job.
 

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Yah, they aren't difficult. The gaskets on the outside handles are structural and can be a bit of a chinese puzzle until you've done a couple, but if you can handle Bimmer windows you should make short work of this.
 

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No, that Infiniti has the same regulator setup as the older Maxes, with the motor and regulator mounted on the metal inner panel as an assembly. The later stuff is different, there's no separate panel and the regulator mounts to the inner door panel with access holes to get at it. They're about the same difficulty to replace a regulator, but an actuator is much easier on later ones like your Altie because you don't need to pull that whole panel loose.
 
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